How is Y. pestis typically transmitted?
Answer: Rat-flea bite/contact with infected animal (bubonic plague) or via respiratory aerosols (pneumonic plague)
What diseases does Y. pestis cause?
What diseases does Y. pestis cause?
Answer: Bubonic plague (most common), septicemic plague, and pneumonic plague
Describe the morphology of Yersinia pestis:
Describe the morphology of Yersinia pestis:
Answer: Nonmotile, bipolar staining pleomorphic gram-negative coccobacillus
Which zoonotic organisms are facultative intracellular organisms?
Which zoonotic organisms are facultative intracellular organisms?
Answer: Francisella, Brucella, and Yersinia
Name the five medically important zoonotic gram-negative rods:
Name the five medically important zoonotic gram-negative rods:
1. Yersinia
2. Francisella
3. Brucella
4. Pasteurella
5. Bartonella
A 70-year-old man with diabetes presents with severe left ear pain and discharge. On physical examination, there is granulation tissue seen in the ear canal.
A 70-year-old man with diabetes presents with severe left ear pain and discharge. On physical examination, there is granulation tissue seen in the ear canal.
Answer: Pseudomonas is the most common cause of malignant otitis externa.
A 10-year-old girl with cystic fibrosis presents with 2 days of high fever and a cough productive of purulent green sputum. On chest x-ray (CXR) there is a left upper lobe (LUL) infiltrate. What is the most likely pathogen contributing to her symptoms? Appropriate treatment?
A 10-year-old girl with cystic fibrosis presents with 2 days of high fever and a cough productive of purulent green sputum. On chest x-ray (CXR) there is a left upper lobe (LUL) infiltrate. What is the most likely pathogen contributing to her symptoms? Appropriate treatment?
Answer: Pseudomonas aeruginosa. Treatment with an aminoglycoside and antipseudomonal penicillin (eg, tobramycin and piperacillin) or an antipseudomonal cephalosporin
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