Which statement most accurately describes what happens to proteins that lack an ER signal sequence?

Which statement most accurately describes what happens to proteins that lack an ER signal sequence?



  1. They are inserted into the plasma membrane.
  2. They are inserted into the ER membrane but do not enter the ER lumen.
  3. They are released into the cytosol.
  4. They bypass the ER but enter the Golgi apparatus.



Answer: They are released into the cytosol.


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