Typhoid fever is a protracted disease of about 3 weeks. Describe the pathogenesis and symptoms seen in each week:

Typhoid fever is a protracted disease of about 3 weeks. Describe the pathogenesis and symptoms seen in each week:



Week 1

Bacteremia with fever/chills


Week 2

Monocyte involvement with organ inflammation, abdominal pain, and rash


Week 3

Ulceration of Peyer patches, intestinal bleeding, and shock


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